The Yo-Yo Effect and Metabolic Memory

January 5, 2025 ,

autopromo_healthy_en

The no-diet approach

Rather than opting for a restrictive and temporary diet, it is more beneficial in the long term to turn to the no-diet approach which aims to develop a positive relationship with food rather than weight loss at all costs. To learn more, check out our article Intuitive Eating: Putting an End to Diets.

Sources

1. Nordmo M, Danielsen YS, Nordmo M. The challenge of keeping it off, a descriptive systematic review of high-quality, follow-up studies of obesity treatments. Obes Rev. 2020 Jan;21(1):e12949. doi: 10.1111/obr.12949. Epub 2019 Nov 1. PMID: 31675146.

2. Contreras RE, Schriever SC, Pfluger PT. Physiological and Epigenetic Features of Yoyo Dieting and Weight Control. Front Genet. 2019 Dec 11;10:1015. doi: 10.3389/fgene.2019.01015. PMID: 31921275; PMCID: PMC6917653.

3. Hinte, L.C., Castellano-Castillo, D., Ghosh, A. et al. Adipose tissue retains an epigenetic memory of obesity after weight loss. Nature 636, 457–465 (2024). https://doi.org/10.1038/s41586-024-08165-7

4. Zou H, Yin P, Liu L, et al. Association between weight cycling and risk of developing diabetes in adults: A systematic review and meta-analysis. J Diabetes Investig. 2021 Apr;12(4):625-632. doi: 10.1111/jdi.13380. Epub 2020 Aug 28. PMID: 32745374; PMCID: PMC8015818.

5. Mackie GM, Samocha-Bonet D, Tam CS. Does weight cycling promote obesity and metabolic risk factors? Obes Res Clin Pract. 2017 Mar-Apr;11(2):131-139. doi: 10.1016/j.orcp.2016.10.284. Epub 2016 Oct 20. PMID: 27773644.

6. National Task Force on the Prevention and Treatment of Obesity. Dieting and the development of eating disorders in overweight and obese adults. Arch Intern Med. 2000 Sep 25;160(17):2581-9. doi: 10.1001/archinte.160.17.2581. PMID: 10999971.

7. Seganfredo FB, Blume CA, Moehlecke M, et al. Weight-loss interventions and gut microbiota changes in overweight and obese patients: a systematic review. Obes Rev. 2017 Aug;18(8):832-851. doi: 10.1111/obr.12541. Epub 2017 May 19. PMID: 28524627.

8. Thaiss CA, Itav S, Rothschild D, et al. Persistent microbiome alterations modulate the rate of post-dieting weight regain. Nature. 2016 Dec 22;540(7634):544-551. doi: 10.1038/nature20796. Epub 2016 Nov 24. PMID: 27906159.

9. Sanaya N, Janusaite M, Dalamaga M, Magkos F. The Physiological Effects of Weight-Cycling: A Review of Current Evidence. Curr Obes Rep. 2024 Mar;13(1):35-50. doi: 10.1007/s13679-023-00539-8. Epub 2024 Jan 3. PMID: 38172475.

Pages: 1 2

Author

Tracy L’Allier Ebacher
A University of Montreal graduate and holding a Master's Degree in Medical Research from Griffith University in Australia, Tracy is a Registered Dietitian and active member of the Ordre professionnel des Diététistes Nutritionnistes du Québec (ODNQ). With more than 15 years of experience, she likes to share her knowledge about food in a simple and illustrated way in order to support you in achieving your health goals. Her approach combines the pleasure of eating, intuitive eating and mindfulness. Tracy specializes in adapted nutrition for chronic diseases, weight loss, gastrointestinal health, vegetarianism and veganism.

Leave a Reply

Your email address will not be published. Required fields are marked *

This website uses cookies to give the best user experience, monitor the site performance, offer social networks features, or display advertisements. By clicking "ACCEPT", you consent to the use of cookies in accordance to our privacy policy.